EFFECT OF TERMINALIA BELLERICA FRUIT ROXB ON ALLOXAN INDUCED DIABETIC RELATED ATHEROSCLEROSIS ON WISTAR ALBINO RATS 

ABSTRACT

To investigate the effect  of Terminalia bellerica (Family: Combretaceae)fruit extracts on diabetic related atheroclerosis. Different extracts  such as Hexane (HETB), Chloroform (CETB), Ethanol (EETB), Aqueous (AETB)  at the dose of 200mg/kg were administered  to  high fat diet associated with  alloxan induced diabetic hyperlipidemic rats. It was found that the fruit extracts significantly reduce the  Total cholestrol, LDL, VLDL levels and significant increase in  HDL Levels. Aqueous extract of Terminalia bellerica fruit extracts, <a href="http://www.aucheaptrx.com/">cheap trx for sale</a> have more significant activity on reducing the Total cholestrol, LDL,VLDL levels and significantly increase in  HDL Levels. Histopathology results also proves  that there is a less accumulation of lipids in the walls of the arch of aorta in aqueous extract.

 KEY WORDS: Diabetes,  Atheroclerosis, High fat diet.  

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