PHYTOCHEMICAL INVESTIGATION AND ANTIBACTERIAL ACTIVITY OF THE FRUITS OF ALSTONIA SCHOLARIS 

ABSTRACT

The present paper is aimed at the phytochemical analysis and antibacterial activity of the fruits of Alstonia scholaris. The findings of the work revealed that the solvent extract of plant showed the presence of phytochemical constituents like alkaloids, carbohydrates, phenolic compounds, terpenoids,  cardiac glycosides and flavanoids in major amounts while fixed oils and fats, saponins and steroids in lesser amounts. These phytochemicals have reported to have conferred the necessary bioactivity to the plant like the antibacterial activity. However the test of antibacterial activity showed dose dependent inhibition of bacteria with maximum antibacterial activity in case of benzene and butanol solvent inhibiting Lactobacillus lactis and Staphylococcus aureus respectively. However least antibacterial activity was seen in case of hexane extract and aqueous and methanolic extract showed cheap trx for sale overall higher activity compared to other extract. The results of antibacterial activity are quite similar to standard antibiotic chloramphenicol thus indicating the possible cure of bacterial pathogenic diseases using these plant extracts in future.

Keywords: Alstonia scholaris, antibacterial activity, pathogenic, phytochemical analysis.