EVALUATION OF ANTIFUNGAL EFFECT ON ETHANOLIC EXTRACT OF LEPIDIUM SATIVUML.SEED 

ABSTRACT

Lepidium sativum is one of the medicinal plants having great potency in treating certain common diseases traditionally. This research aim at testing the antifungal activity of ethanolic extract of Lepidium sativum seeds against Fusarium equiseta, Aspergillus flavus, Alternaria alternate in Potato Dextrose Agar (PDA). Qualitative phytochemical screening showed presences of essential oil, phenolic compounds, alkaloids, Glycosides, tannins, amino acid, steroids. The antifungal activity of ethanolic extract of Lepidium sativum was evaluated by employing various concentration (2-8mg).All the concentration of seed extract inhibited the fungal growth. Among different doses, the diameter of inhibition zone ranged from 4 to 22 mm in various fungal species. Hence, the results of the present investigations trx canada indicate the Lepidium sativum extracts possess antifungal activity that can be exploited as an ideal treatment for future fungal disease.

Keywords: Lepidium sativum, Antifungal activity, Potato Dextrose Agar (PDA), Inhibition zone, Phytochemical screening.