MULTI DRUG RESISTANCE: A NEED TO BE ATTENTION

ABSTRACT  

Multidrug resistance as the ability of a living cell to show resistance to a wide variety of structurally and functionally unrelated compounds. It showed 'intrinsic' when the disease is refractory to chemotherapy from the outset, or 'acquired' when the disease becomes insensitive to treatment upon relapse. In mammals, tumors, which are initially sensitive to cytotoxic agents, often develop resistance to a broad spectrum of structurally unrelated drugs. The widespread occurrence of multi drug resistance in tumor cells represents a major impediment to successful cancer chemotherapy. Multiple drug cheap trx resistance is a condition enabling a disease-causing organism to resist distinct drugs or chemicals of a wide variety of structure and function targeted at eradicating the organism. Organisms that show multidrug resistance can be pathologic cells, including bacterial and neoplastic (tumor) cells.

Keywords :- MDR, Resistance, Antibiotic resistance, Gene transfer, Drug Resistant.