PHARMACOGNOSTIC AND PRILIMINERY PHYTOCHEMICAL INVESTIGATION ON LEAF EXTRACTS OF Myristica dactyloides Gaertn.

 ABSTRACT

Myristica dactyloides (Syn: Myristica laurifolia Hook.,) belongs to the family myristicaceae is  indigenous medicinal plants and used very  commonly in the management of various diseases like diabetes, bronchitis, constipation and in various skin ailments. Present work is related to standardization of Myristica dactyloides by using pharmacognostic (macroscopy, microscopy and physical constants) and phytochemical investigation on leaf of Myristica laurifolia. The leaves of Myristica dactyloides were extracted with different organic solvents in increasing order of polarity. The results of the preliminary investigation revealed the presence of alkaloids, steroids, flavonoids, terpenoids, glycosides & carbohydrates. The Methanol, Acetone and chloroform extracts were studied and the phytochemical compounds were isolated by using thin layer and column chromatography. The chemical structures of the isolated compounds were established by spectroscopic techniques such as UV, IR spectroscopy. This was again confirmed by co TLC with standard sample. The aim of the present study was focused on the pharmacognostical, physicochemical and phytochemical properties were carried out, which would like to facilitate quick identification and cheap trx canada for sale selection of the drug from various adulterates. All the parameters were studied according to the WHO and pharmacopoeia guidelines to standardize the Myristica dactyloides.

Key words: Myristica dactyloides, Pharmacognostic evaluation, Physico-chemical characterization, TLC, Spectroscopy.