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PROTECTIVE EFFECT OF CHENOPODIUM ALBUM ETHANOLIC EXTRACT AGAINST ASPIRIN INDUCED PEPTIC ULCER IN RAT MODEL
ABSTRACT
Chenopodium album, is a commonly used plant in Indian traditional medicine belongs to family Chenopodiaceae. In our study, anti-ulcer activity of its ethanolic extracts of whole plant were investigated using Wistar rats as animal models. Extracts were also subjected to phytochemical analysis and found to contain Carbohydrates, Proteins, Flavonoids, Tannins and phenolic compounds. Chenopodium album alcoholic extracts were found to be non-toxic up to 1500 mg/kg dose level. During conï¬rmation of the claimed anti-ulcer activity, treatment with two different alcoholic extracts in 200mg and 400 mg/kg showed signiï¬cant reduction in ulcer index, free acidity as well as total acidity cheap trx canada in pylorus ligated rats. However, profound reduction in all these indices was observed with both of the doses. But higher dose of extract showed relatively significant protection.
Key words: Chenopodium album, Ulcer index, Antiulcer activity.
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