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AN EVALUATION OF THE ANTIBACTERIAL ACTIVITY OF ROOT EXTRACTS OF MANILKARA ZAPOTA AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI
ABSTRACT
Manilkara zapota powdered root material was extracted using water. Phytochemical screening of the crude extracts revealed the presence of alkaloids, glycosides, saponins, tannins, carboxylic acids. This presence of the bioactive constituents have been linked to the antimicrobial activity of the plant material against Staphylococcus aureus (gm+ve) and Escherichia coli (gm–ve) using agar cup plate method. Minimum inhibitory concentration values ranged from 25-100 mg/ml. The plant can be used as a source of oral drugs to fight infections against susceptible bacteria.
Key words: Manilkara zapota root, Antibacterial activity, Staphylococcus aureus, Escherichia coli, Aqueous extract.
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