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IN VITRO ANTIMICROBIAL, ANTITUMOR AND CYTOTOXIC ACTIVITIES OF METHANOLIC EXTRACT AND ITS FRACTIONS OF ACANTHOLIMON LONGISCAPUM
ABSTRACT
The aim of the present investigation deals with biological evaluation Acantholimon longiscapum leaves. For this purpose different biological assay of methanolic extract (Crude) and its fractions that are chloroform fraction, n-hexane fraction, Ethyl acetate fraction, n-butanol fraction and aqueous fraction were carried out. The results from the agar diffusion method indicated that Crude showed maximum antibacterial activity against Staphylococcus aureus with the inhibition zone (31.18±0.01mm). On the other hand, Crude showed maximum activity against Candida albicans and Candida glaberata with % inhibition of (76.10%±0.02%) and (82.02%±0.11%) respectively. On the other hand, Crude also showed tremendous Antitumor activity with % inhibition 85.23% as comparable to the standard drug.
Key words: Antimicrobial, Antitumor, Cytotoxic, Acantholimon longiscapum leaves.
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