ANTI-INFLAMMATORY EFFECT OF METHANOLIC EXTRACT OF TAMILNADIA ULIGINOSA (RETZ.) ROOTS

ABSTRACT

                To evaluate the anti-inflammatory activity of the roots of Tamilnadia uliginosa. Anti-inflammatory activity was conducted by using Carrageenan induced rat paw oedema model. The thickness of paws of rats was measured every hour up to 5 hrs for methanolic extract at doses of 100, 200 and 400mg/kg by volume displacement method, using plethysmometer. All doses of the extract (methanol) from the roots of Tamilnadia uliginosa  showed significant percentage of inhibition on Carrageenan induced paw oedema; methanol extract from the roots of Tamilnadia uliginosa  at dose 400mg/kg produced significant (P<0.001) percentage of inhibition when compared to other doses. Tamilnadia uliginosa roots extract (methanol), showed significant anti-inflammatory activity.

Key words: Tamilnadia uliginosa, Roots, Anti-inflammatory activity.