ANTIOXIDANT ACTIVITIES OF THE LEAVES OF THUNBERGIA COCCINEA WALL

To evaluate the in-vitro antioxidant potential of methanolic extract of Thunbergia coccinea. The leaves of Thunbergia coccinea Wall were dried and powdered. The methanol extract of the sample were prepared by using Soxhlet apparatus. The extract was filtered using Whatman filter paper No 42 (125 mm) and the extract was evaporated under reduced pressure using Rotary Vaccum evaporator . Anti-oxidant analysis such as DPPH, Hydroxyl, Superoxide and Nitric oxide of the above extract was done by standard methods. The IC50 values of scavenging activities of METC on DPPH, Hydroxyl, Superoxide and Nitric oxide radicals were found to be, 179.21 mcg/ml, 73.52 mcg/ml, 40.88 mcg/ml and 76.21mcg/ml as compared to Ascorbic acid and Gallic acid which were found to be 35.84mcg/ml and 45.45mcg/ml respectively. The data obtained in the present study suggests that the extracts of Thunbergia coccinea leaves have potent antioxidant activity against free radicals, prevent oxidative damage to major biomolecules and afford significant protection against oxidative damage.