HEPATOPROTECTIVE ACTIVITY OF FENUGREEK (TRIGONELLA FOENUM - GRAECUM) AND GARLIC (ALLIUM SATIVUM) AGAINST HEPATOTOXICITY INDUCED IN DIFFERENT MICE AND RATS EXPERIMENTAL MODELS – A REVIEW

Herbal medicine is one of the oldest forms of health care known to mankind for many generations. Various research findings have given much attention to fenugreek (Trigonella foenum graecum) seeds and garlic (Allium sativum) for their hepatoprotective effect on toxicity induced on rat liver cells. The objective of this review is to provide summarized report of the existing data on fenugreek seeds and garlic for their hepatoprotective effect in different experimental models. Various reports cited in this article represent that fenugreek seeds and garlic have hepatoprotective effect by lowering and stabilizing the biochemical parameters of liver function tests that are elevated due to liver damage. The findings showed that fenugreek seeds and garlic have a vital role in antioxidant effect, by inhibiting or scavenging free radicals prevent lipid peroxidation, hepatic protective effect and restoration of hepatic damage.