CLINICAL UTILITY OF LIPID PROFILE, HOMOCYSTEINE IN EARLY STAGES OF ACUTE MYOCARDIAL INFARCTION

Coronary artery disease is now a major health problem in India. In past few decade, the battle to reduce the incidence of CAD has led the researchers to look for various clinical markers, which would help early diagnosis of the diseases. The present study was undertaken to assess the levels of lipid profile like Triacylglycerol level, Cholesterol , LDL and Homocysteine in selected Myocardial infarction (MI) patients. Fasting blood samples were taken from 50 MI patients (30 males and 20 females) and compared with age matched controls. Blood samples from MI patients were taken at Zero hours (i.e; at the time of admission),1 hour and after 6 hours. By the end of 6 hrs, TGL,LDL and Homocysteine increases whereas cholesterol does not showed significant difference when compared with controls. Thus the present study indicates a strong association between the lipid profile and homocysteine level with the AMI and thus implying possible risk factors for MI