EVALUATION OF ANTIOXIDANT, ANTI-LIPID PEROXIDATION,
AND ANTI-DIABETIC PROPERTIES OF ETHANOL EXTRACT OF
ZAPPANIA URTICIFOLIA (EEZU): A PHYTOCHEMICAL AND
ENZYMATIC STUDY
The study aimed to investigate the antioxidant, anti-lipid peroxidation, and anti-diabetic properties of the ethanol extract of
Zappania urticifolia (EEZU). Fresh plant material of Zappania urticifolia was collected and authenticated, followed by
ethanol extraction to obtain EEZU. Phytochemical analysis revealed the presence of alkaloids, flavonoids, and tannins in the
extract. The anti-diabetic potential of EEZU was evaluated through ?-amylase and ?-glucosidase inhibition assays. The
results indicated that ?-amylase inhibitory activity of EEZU was concentration-dependent, with the IC50 value determining
the concentration required for 50% inhibition. Comparison with the standard drug, Acarbose, demonstrated the effectiveness
of EEZU, particularly at higher concentrations. These findings align with existing literature on the medicinal potential of
Zappania urticifolia, suggesting its value as a natural therapeutic resource. The study provides a comprehensive
understanding of the potential therapeutic benefits of EEZU, highlighting its relevance in natural medicine for managing
oxidative stress and diabetes