EVALUATION OF ANTIOXIDANT, ANTI-LIPID PEROXIDATION, AND ANTI-DIABETIC PROPERTIES OF ETHANOL EXTRACT OF ZAPPANIA URTICIFOLIA (EEZU): A PHYTOCHEMICAL AND ENZYMATIC STUDY
The study aimed to investigate the antioxidant, anti-lipid peroxidation, and anti-diabetic properties of the ethanol extract of Zappania urticifolia (EEZU). Fresh plant material of Zappania urticifolia was collected and authenticated, followed by ethanol extraction to obtain EEZU. Phytochemical analysis revealed the presence of alkaloids, flavonoids, and tannins in the extract. The anti-diabetic potential of EEZU was evaluated through ?-amylase and ?-glucosidase inhibition assays. The results indicated that ?-amylase inhibitory activity of EEZU was concentration-dependent, with the IC50 value determining the concentration required for 50% inhibition. Comparison with the standard drug, Acarbose, demonstrated the effectiveness of EEZU, particularly at higher concentrations. These findings align with existing literature on the medicinal potential of Zappania urticifolia, suggesting its value as a natural therapeutic resource. The study provides a comprehensive understanding of the potential therapeutic benefits of EEZU, highlighting its relevance in natural medicine for managing oxidative stress and diabetes
Copyright www.pharmaweb.co.in © 2010. All rights reserved.

International Journal of Phytopharmacology (onlineijp) is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. Based on a work at http://onlineijp.com/.Permissions beyond the scope of this license may be available at http:// onlineijp.com /