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ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF METHANOLIC
EXTRACT OF ARGEMONE MEXICANA LEAVES
Abstract
A total of 6 bacteria, two Gram positive (Bacillus subtilis MTCC 619 and Staphylococcus aureus MTCC 2940), four Gram negative bacteria (Escherichia coli MTCC 118, Pseudomonas aeruginosa NCIM 2074, Proteus vulgaris NCIM 2817, Salmonella typhi NCIM 2501) and 4 fungi (Aspergillus niger NCIM 589, Fusarium moniliforme NCIM 1099, Candida albicans NCIM 3100 and Mucor plumbeus NCIM 984) were tested for antibacterial and antifungal activity against methanolic extracts of leaves of Argemone mexicana by agar well diffusion method. Among different concentrations (40µl, 70µl, 100µl) of leaf extracts studied 40µl showed no activity against bacteria and fungi. Whereas, 100µl showed maximum inhibition against all the test organisms under investigation. While, 70µl showed activity against Staphylococcus aureus, Escherichia coli and Proteus vulgaris and all the fungi under study.
Key words: Argemone mexicana, antibacterial, antifungal activity.
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