Evaluation of Analgesic and Anti-Inflammatory properties of Chloris barbata (SW.)

Abstract

                The petroleum ether extract of Chloris barbata (SW.) was evaluated for analgesic and anti-inflammatory activity at the doses of 200 and 400 mg/kg body weight. The tail immersion and acetic acid writhing response in mice were used to assess analgesic activity. The acute toxicity study of the extract had shown no sign of toxicity up to a dose level of 2000mg/kg body weight.  Carrageenan induced paw edema in rats, which is an acute model used to assess anti-inflammatory activity. <a href="http://www.aucheaptrx.com/">cheap trx for sale</a> The extract has inhibited paw edema in dose related manner. A dose dependent analgesic action was obtained against tail immersion and writhing test indicating that analgesic activity may be involved in the inhibition of the pain. Thus the extract of Chloris barbata (SW.) possesses significant analgesic and anti-inflammatory activities.

KEY WORDS: Chloris barbata (SW.), anti-inflammatory, analgesic, writhing.